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Here’s a comprehensive overview of the field of bioinformatics using Python, covering key concepts, tools, and applications:
1. Introduction to Bioinformatics:
- Bioinformatics is an interdisciplinary field that combines biology, computer science, and statistics to analyze and interpret biological data.
- Python has become a popular programming language in bioinformatics due to its readability, versatility, and a rich ecosystem of libraries.
2. Biological Data Handling with Python:
Biopython Library:
Biopython
is a comprehensive library for biological data processing, offering modules for working with sequences, structures, and annotations.- Functions for reading and writing various biological file formats (
FASTA
,GenBank
,PDB
).
3. Sequence Analysis:
- DNA, RNA, and Protein Sequences:
- Python is used to manipulate and analyze biological sequences.
- Sequence alignment, searching for motifs, calculating GC content, and extracting features.